Chronic treatment requires sustainable financing
Another study, not yet published, is SURMOUNT-OSA, a clinical trial of 52-weeks that examined the efficacy and safety of TZP versus placebo in obese participants and an established OSA diagnosis for treatment of moderate and severe OSA (102)
The extended half-life means timing matters less than with shorter-acting peptides
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However, individuals with kidney disease, heart failure, or uncontrolled hypertension should consult their physician before increasing sodium intake above 2,300mg daily
Among the participants, most of whom were women, 148 were on Ozempic, 217 were on Wegovy, and 46 were on Mounjaro