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The B12-IF complex travels through the intestine until it comes to the last part of the small intestine called the ileum
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Initial brightness and radiance improvements may appear within 2-4 weeks
Megaloblastic anemia due to B12 deficiency is either caused by inadequate intake, in which case oral supplementation is sufficient, or poor absorption potentially due to a reduction in intrinsic factor. Intrinsic factor, which is synthesized by cells in the stomach, is secreted into the gastrointestinal tract to bind dietary B12 and facilitate its absorption (Wickramasinghe 2006)
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