Due to its high structural similarity, the peptide has been incorporated into mechanistic studies examining melanocortin receptor selectivity, agonist potency, and downstream signaling dynamics
and energy metabolism by providing energetic substrates to neurons
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Human glutathione S-transferases- and NAD(P)H:quinone oxidoreductase 1-catalyzed inactivation of reactive quinoneimines of amodiaquine and N-desethylamodiaquine: possible implications for susceptibility to amodiaquine-induced liver toxicity
Ruijter GJG, van de Vondervoort PJI, Visser J