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Under inflammasome related pyroptotic stress, caspase-1 and gasdermin D promote mtDNA escape into the cytosol, then drive intraluminal vesicle formation that enables mtDNA loading into intraluminal vesicles (ILVs) and release via exosomes
Wynendaele, E., De Spiegeleer, B., Gevaert, B., Janssens, Y., Suleman, S., Cattoor, S., Saunders, J
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15, 16 In the following paragraphs, we will summarize the role of different enzymatic sources of oxidative stress that are felt to be relevant to hypertension, and we will discuss how ROS may alter vascular function and contribute to the development and progression of hypertension
After extracting as m u c h meaning from the document as possible, a child will naturally feel the need to systematize and .rank-order the interpretations he has discovered
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