doi: 10.4158/EP12247.OR 7 Schernthaner-ReiterMHSiessGesslAScheubaCWolfsbergerSRissPet al
But recent data suggest that not everyone is so adept
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This relatively small GPCR family is characterized by a long extracellular ligand-binding domain stabilized by three disulfide bridges formed by six highly conserved cysteine residues, seven -helical transmembrane domains, universal for all GPCRs and an intracellular C-terminal domain, responsible mostly for receptor internalization due to the presence of multiple phosphorylation sites [22, 23]
It is moderate pressure, not the most aggressive weve seen, but the discount promise is, functionally, bait