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doi: 10.3389/fvets.2023.1093274 Received 08 November 2022 Accepted 20 January 2023 Published 16 February 2023 Volume 10 - 2023 Edited by Ayman Abdel-Aziz Swelum, Zagazig University, Egypt Reviewed by Amany Abdel-Rahman Mohamed, Zagazig University, Egypt
Kim MP, Correa AM, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Erasmus JJ, Swisher SG
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up to 56 days , but refrigeration is recommended
Significantly, a compound denoted as melatonin-trientine, covalently synthesized with melatonin and the metal ion chelator trientine, demonstrated the capacity to elevate the expression of IDE in a murine AD model, and decreased A deposition and neuronal degeneration in the brains of the APP/Presenilin 1 mice [65]
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