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ESC Heart Fail 7 , 37723781 (2020)

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In vivo pharmacokinetic measurements The pharmacokinetic assessment was conducted using a total of eight male DIO C57BL/6J mice ( n = 4 per subgroup)

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However, to make matters more complex, there was moderate heterogeneity among the included trials, with an I 2 of 43%

All indexes of the pilot-scale test samples and the three verification samples in the detection batch are in accordance with the drawn draft of the quality standard of the injection reduced glutathione, and the number, the position, the single impurity content and the total impurity content of the impurities of the samples in several batches are basically consistent, which indicates that the difference between the batches of the samples is small