Therefore, future studies should focus on the molecular and cellular mechanisms elicited by various types of thermal water, using various matrices, such as primary cell cultures, tissue explants obtained from diseased skin, or complex cellular models, such as 3D models of primary cell culture, to investigate the effects of specific types of thermal water for the treatment of certain skin diseases
Ueda M et al
Trincadeira berries upon infection with Botrytis cinerea
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