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The genetic correlates relate primarily to variants in the genes coding for transporters controlling plasma UA, yet such presumed functional variants will also influence, through the same proteins, the transport of UA into the brain and subsequently into neurons and glia, as described below
HUBERMAN: And this is very important to understand because unlike a lot of our discussion on this podcast about dopamine or about specific hormones like testosterone or estrogen, when we talk about peptides, especially therapeutic peptides, oftentimes we're talking about a single peptide that does a bunch of different things depending on the cell type, the time of day or night that that peptide is present, and even the different so-called downstream effects of the peptide
Retrieved May 2, 2025, from ScienceDirect
pastoris secreted recombinant DSIP-CBBBP on neurotransmitter levels, we quantified the concentrations of melatonin, serotonin, dopamine, and glutamate in the mouse serum
