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Needle insertion: Pinch a fold of skin (12 inches) between thumb and forefinger

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[9] That is an actual clinical regimen, not a research convention

Trial registration Iranian Registry of Clinical Trials IRCT20201129049534N1

In patients with DM2 the incretin response is diminished, but the insulinotropic effect of GLP-1 is conserved.28 Under normal conditions GLP-1 has a short half-life (approximately 2 min), as it is rapidly degraded by dipeptidylpeptidase 4, so GLP-1 analogues resistant to this enzyme have been developed for the treatment of DM2.29 arGLP-1: glucagon-like peptide 1 receptor agonist

Source: Droge, W