Phase 3 trials typically take several years to complete, and results from the TRIUMPH programme are anticipated broadly in the 20252027 timeframe based on estimated completion dates registered on ClinicalTrials.gov, though this is subject to change
71 These data, together with the finding of no effect of prior weight-reduction strategies on hard outcomes in HF, signify very likely beneficial effects of GLP-1RAs that are independent of weight loss
Inflammatory caspases are innate immune receptors for intracellular LPS
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4 A higher dose of 5 mg daily is recommended for those at increased risk of neural tube defects, and is available on prescription
