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It is also authorised for use in weight loss and weight management in adults aged 18 and over, alongside a reduced-calorie diet and increased physical activity

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Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

This limits access for many patients seeking GLP-1 drugs for weight management

Cardiovascular Benefits : Some GLP-1 RAs, including semaglutide, have demonstrated cardiovascular benefits by reducing the risk of heart-related complications in individuals with type 2 diabetes

Excessive drinking has been linked to poor sperm parameters and hormonal imbalances