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Following this, the SURPASS-3 trial evaluated tirzepatide in patients with T2DM inadequately controlled by metformin, with or without SGLT2 inhibitors

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Real-time qPCR BF muscle and liver biopsies obtained from animals that received a 1-week infusion of either oIGF-1 or SAL were used for real-time qPCR

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Elevated insulin levels can drive excess androgen production, which in turn contributes to irregular ovulation and other symptoms of PCOS ( 9 )