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FIGURE 7 The strong role of severe oxidative stress, reduced antioxidant defenses like GSH with increased lipid peroxidation and malondialdehyde generation (213), lipid, protein and DNA oxidation with increased apoptosis and necrosis in atherosclerosis as a major cause of cardiovascular diseases and stroke, supports the use of complementary and alternative medicines, dietary supplements, and antioxidants with hardly any adverse effect, able to restore homeostasis reversing oxidative stress (214)

This is particularly relevant for patients in high-stress professions or those experiencing age-related sleep disturbances

Why doesnt Sinclair take NAD+ directly

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Some natural sources that can help increase glutathione levels are turmeric, sulfur-rich foods, milk thistle, avocados, and almonds

doi:10.3390/antibiotics12081304 Anes J, McCusker MP, Fanning S, Martins M