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PMID: 67 BadalVDVaccarielloEDMurrayERYuKEKnightRJesteDVet al

We and others have recently shown that the distribution of intrinsic disorder propensity within the amino acid sequence of mature IGF-1 is markedly different compared to E-domains 5,13

FDA stated it lacked safety-related information for certain other injectable routes, meaning the agency did not have enough information to determine whether harm would occur through those routes

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