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Rotating injection sites with each dose helps prevent lipodystrophy, which is the breakdown or buildup of fat tissue at the injection site

This is the single biggest practical difference between the two drugs for most patients

If you have to miss more than two weeks of doses, your provider may suggest restarting at a lower dose to avoid a sudden onset of side effects

Chen K, Chen L, Shan Z, Wang G, Qu S, Qin G, et al

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and that tobacco products are regulated