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Retatrutide is a synthetic incretin-mimetic peptide and triple-receptor agonist that activates the GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1) and glucagon receptors simultaneously, originally developed by Eli Lilly under the code LY3437943 [1][3]

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So I recommend taking a short break after 4 months