future health semaglutide FuturHealth to Deliver Affordable, FDA-Approved GLP-1s Nationwide Semaglutide Weight Loss Program |

GLP-1, GIP & Inflammation: What These Medications Really Do and What They Dont Joshua Silva, MD Dec 5, 2025 7 min read Updated: Jan 27 Medically authored by Joshua Silva, MD | Evidence-Based Weight Loss at Potere Health MD Quick Answer GLP-1 and GLP-1/GIP medications (such as semaglutide and tirzepatide ) can lower metabolic inflammation by improving insulin resistance, reducing visceral fat, and lowering inflammatory biomarkers such as C-reactive protein (CRP) ., They can also improve cardiometabolic risk markers (e.g., blood pressure) and, for tirzepatide, can improve atherogenic lipoprotein measures including apoB and triglyceride-rich lipoproteins in clinical research settings., They do not treat autoimmune diseases or fibromyalgia directly

Instead of 2 big meals, eat 45 small ones

Tracking calories for even a few days provides clarity on whether this is the issue

Originally approved to help people with Type 2 diabetes, the class of medications known as GLP-1 agonists and dual GIP/GLP-1s quickly acquired a reputation for helping people shed stubborn pounds

doi: 10.1016/J.IJBIOMAC.2023.126706 55 GhaleiS.HandaH

Topiramate and semaglutide do not have direct drug-drug interactions, but they amplify overlapping side effects including nausea, dizziness, and cognitive changes