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The development of gene editing tools has evolved from homologous recombination to first-generation zinc finger nucleases (ZFNs), second-generation transcription activator-like effector nucleases (TALENs), and the more recent clustered regularly interspaced short palindromic repeats (CRISPR)-associated system, which has revolutionized life sciences 97

Holterman CE, Thibodeau JF, Towaij C, Gutsol A, Montezano AC, Parks RJ, et al

Because of this, limonene is often avoided by people with sensitive skin

The question of which is better depends partly on what result you are actually trying to achieve