Though not FDA-approved for weight loss, it's used off-label to target stubborn fat areas
Clinical trials showed joint pain occurred at similar rates in tirzepatide and placebo groups, and joint inflammation is not a known pharmacologic effect of GIP or GLP-1 receptor activation
At the same time, it fine-tunes which collagen-clearing enzymes are active, striking a balance between breaking down old tissue and building new tissue, while also calming inflammation
The number of serious issues that occurred, like cancer or infection, was slightly lower in the semaglutide group
Who, When and How
The best GLP-1 weight loss program depends on your specific needs, whether you prioritize cost, insurance coverage, comprehensive coaching, or straightforward access to compounded medications