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Some continue for several months
Conversely, the coadministration of weekly high-dose vitamin D (cholecalciferol 50,000 IU) with antidepressant therapy was associated with significantly improved fatigue scores at weeks 4, 8, and 12 in a case-control study [130]
They are well-tolerated but their ability to lower blood sugar is modest and they generally do not cause weight loss
Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg (primarily for tolerability) and gradually titrated upward every 4 weeks based on glycemic response and tolerability
These habits require time to establish, which is why developing them during active treatment rather than trying to adopt them after stopping makes sense
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