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Increased iron metabolism in cancer cells is orchestrated by upregulation of iron import via TFR1 [58,59,60,61] and DMT1 [62], and/or downregulation of iron export via FPN1 [60] (Fig

Funding The research was supported in part by Grants-in-Aid for Challenging Exploratory Research and Scientific Research (B) from the Japan Society for the Promotion of Science (JSPS KAKENHI Grant Numbers JP26660218, JP21H02347, and JP24K01911, respectively) and by grant funds from the Uehara Memorial Foundation and Ito Foundation (all to R

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