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Vitamin C is essential for collagen synthesis, with research supporting 500-1000 mg daily during healing periods

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10.1093/emboj/cdg194 EMBO J

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But TB-500 as sold in grey markets is not the same thing as a well-characterized pharmaceutical product, and the FDAs Category 2 listing includes Thymosin Beta-4, Fragment (LKKTETQ) as a substance raising significant safety risks in compounding contexts