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Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel JC, Decker H, et al

Clinical research involving approximately 900 participants across six human trials has validated AOD-9604 s selective fat-targeting effects

10.3389/fcvm.2022.1019120 80

Building on these research findings, Eli Lilly developed a dual agonist targeting GLP-1R/GIPR, called tirzepatide, which was approved by the FDA in 2022 and showed promising therapeutic effects for T2D and obesity