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This stops deficiency from coming back

Warnings Patients who have early Leber's disease (LHON) a hereditary disease that causes optic nerve atrophy have been found to suffer severe and swift optic atrophy when treated with vitamin B12

For more frequent symptoms, histamine-2 receptor antagonists (H2RAs) such as famotidine may be used, though patients should be counseled that these medications may take 30-60 minutes to provide relief

Combination therapy erases this gap while adding complexity and cost

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