While enabling patients to lose weight, a knock-on effect is that the risk of cardiac events, such as heart attacks and strokes, are reduced
Blinded allocation, centralized measurement of renal endpoints, and high retention rates support confidence in directionality of effect, while limitations arise primarily from study duration, sample size, and surrogate endpoints (albuminuria, eGFR slope)
Patients should contact their GP or diabetes care team if gastrointestinal symptoms are severe, persistent, or significantly impacting quality of life and nutritional intake
Some of the discourse has, candidly, veered into clickbait territory (see: Ozempic Vulva, Ozempic Earlobes), but there is actually a need for innovation around Ozempic Face, a zeitgeist-y catchall for gauntness and skin laxity that can often accompany large weight loss
The interaction is specifically with absorption of pills
Springer US, Boston, MA (1982) Lee YO, Do SH, Won JY, Chin YW, Chewaka LS, Park BR, Kim SJ, Kim SK