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While this popularity has been a financial boon for Novo Nordisk, it has unfortunately resulted in an Ozempic shortage

He did note that stacking multiple medications, including SGLT2 inhibitors and GLP-1 receptor agonists, can be challenging given their expense, noting that some patients can barely afford one. Clinically, Edmonston said that for doctors faced with choosing between treatments, their data suggest an SGLT2 inhibitor is likely better than a GLP-1 receptor agonist if a patients primary concern is decreasing the risk of kidney dialysis

Masamune A, Kikuta K, Watanabe T et al

Barelle CJ, Priest CL, Maccallum DM, Gow NA, Odds FC, Brown AJ

Gallbladder Disease: Plaintiffs have reported severe gallstones and cholecystitis (gallbladder inflammation), in many cases requiring emergency surgery to remove the gallbladder