Since AD-like pathological lesions such as A deposition can be recognized in individuals with DS younger than 40 years old and symptoms of cognitive impairment due to AD exponentially increases from this age, DS has been regarded as a young model of AD 1,6,11
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It may also be caused by specific medical conditions or medication use that affects carnitine levels in the body
Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al
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