On mechanism, the peptides and the small molecules end up at the same destination (Gs activation, cAMP elevation, the canonical incretin pharmacology) but they get there via different binding modes and with different signalling profiles
[4] [5] Readers should note that these figures reflect specific trial protocols and may not represent the doses used in ongoing phase 3 studies or any future licensed product
cDNA generation and RTqPCR cDNA was generated using random hexamers and SuperScript II reverse transcriptase (Invitrogen, 18064-014), according to the manufacturers protocol
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