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The evidence supporting GLP-1 medications for weight loss and metabolic health is robust
Researchers have not identified a lethal dose even at concentrations far exceeding therapeutic ranges
Some research-grade substances have purity levels as low as 60%.22 If you were to introduce such a substance into your body, your immune system could interpret it as a threat and mount a potentially life-threatening response a state called immunogenicity.23 But with pharmaceutical-grade peptides, youre dealing with purity levels of at least 98-99%
A newer drug of this class is semaglutide (sold under the brand name Wegovy), which was approved in 2021 and was found, on average, to reduce weight by 15% in one clinical trial where people took the drug for 68 weeks
This information can support a more informed conversation with your provider about whether dual-receptor therapy aligns with your genetic profile
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