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Studies in Neurospora crassa

Parmigiani, A

Incretin mimetics have demonstrated safety and efficacy in advanced kidney disease, however multiple studies have shown that use of GLP1-RA have shown improvements in glycemic control, body weight reductions, improved beta cell function, and decreased incidence hypoglycemia as compared to DPP4i in a general diabetes population 26,27,28,29,30,31 , effects which might explain the reduction of acute healthcare utilization observed in this study of patients with CKD treated with GLP1-RA as compared to DPP4i

10.1016/j.metabol.2016.02.014 140 MuthennaP.RaghuG.KumarP

Chrysin attenuates the Nlrp3 inflammasome cascade to reduce synovitis and pain in koa rats

Importantly, gradual dose escalation significantly reduced GI side effect rates