Participants also recorded meaningful improvements in blood pressure, triglycerides, non-HDL cholesterol, and high-sensitivity C-reactive protein, a marker of inflammation
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Less common side effects may include abdominal pain , constipation , and changes in appetite
Severe allergic reactions are very rare and almost exclusively associated with injectable rather than oral B12
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The Office of Dietary Supplements of National Institutes of Health gives fact sheets about certain nutrients, including vitamin B12, in which they clarify that while generally considered safe, there are certain concerns regarding the dosage, form, and stability of the injectable version of vitamin B12 as compared to oral supplements