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A 2024 pilot in interstitial cystitis and a 2021 case series in knee pain reported it as well-tolerated within those small samples
It addresses functional B-vitamin insufficiency, particularly during periods of stress or increased metabolic demand, while avoiding imbalance that can occur when single B vitamins are given in isolation
The anhydrous form of the compound is highly hygroscopic
In addition, the concentration of cyanocobalamin is detectable in plasma only in smokers due to the increased cyanide exposure of cigarette smoke in combination with the dietary supplement (Domke et al., 2004)
Without diagnosis, a patient may try a peptide for the wrong problem