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Whats particularly interesting is the study design: The trial does not put its eggs in one basket Liver disease is the primary endpoint
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Mice equivalent to 65-year-old humans doubled their running capacity on the treadmill after MOTS-c treatment
Reflux considerations Gastric Sleeve May worsen reflux in some patients
This has several downstream effects: slower gastric emptying (food stays in the stomach longer, extending fullness), reduced appetite signalling in the hypothalamus, and improved insulin sensitivity, which helps stabilize blood sugar and reduce cravings linked to glucose spikes and crashes
instead, it reflects a complex interplay of price sensitivity, personal goals, and systemic challenges
