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Neuro Oncol 20(11):15051516 Masiero M et al (2013) A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis

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This is a compound where the preclinical signal is strong, but the clinical confirmation is incomplete

Survival of Her2/neu mice was increased by treatment with CCXC872, a small molecule antagonist targeting CCR2

Pernicious anaemia is an autoimmune condition that prevents the binding of vitamin B12 with intrinsic factor and is a common cause of vitamin B12 deficiency

Once a vial is opened, refrigeration (28 C) is recommended per typical laboratory SOPs to extend usable life within the 28-day post-puncture window