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This observation suggests that DET1 interacts with both COP1 and Ube2e proteins, facilitating the presentation of Ube2e proteins by DET1 claw to the COP1 RING dimer

The permeability study demonstrated enhanced BBB (in vitro model) permeability mediated by lactoferrin receptor-targeted transcytosis, showing a 2.7-fold increase in fluorescence intensity for lactoferrin-conjugated nanoparticles compared to non-functionalized ones

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donor 2: i , k ) and treatment durations (6-h: h , i