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Preclinical studies demonstrated that AOD-9604 was generally safe after chronic oral application in rats and cynomolgus monkeys, with no genotoxic concerns identified

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These vitamins are: B1, B2, B3, B5, B6, B7, B9 and B12

This does not mean complete abstinence is required, but regular alcohol consumption will substantially reduce protocol effectiveness

Investigation Areas Enzyme inhibition/interaction screening (in vitro) Pathway signaling and downstream readouts Solubility, vehicle selection, and excipient compatibility Stability studies (temperature/light/oxidation)