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Monitoring also extended to heart rate and blood pressure, as incretin-based therapies can influence cardiovascular physiology

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At the end of the analysis period, an intravenous bolus injection of the green-fluorescent bile salt analogue cholyl-lysyl-fluorescein (CLF) was performed as a positive control as it is known to be rapidly taken up into hepatocytes and excreted into bile canaliculi (Vartak et al

[] Although effective to some extent, these treatments can have limitations