doi:10.1126/science.867037
However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007
Biochemically, the cobalt center can take part in both two-electron and one-electron reductive processes to access the "reduced" (B 12r , +2 oxidation state) and "super-reduced" (B 12s , +1 oxidation state) forms
High purity, CoA verified
The peptide has a half-life of approximately 46 hours, meaning it clears the system relatively quickly compared to longer-acting peptides like CJC-1295 or tesamorelin
Retrieved June 11, 2025, from Grant, R., Berg, J., Mestayer, R., et al