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(Francque et al., 2021, NEJM, PMID 34670042.) GLP-1GIPLani in this paper was dosed at 10 nanomoles per kilogram per day

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Glucagon-Like Peptide-1 Receptor (GLP-1 R) is a key component of the GLP-1 signaling pathway , which plays a crucial role in glucose homeostasis , insulin secretion , and regulation of appetite

Additionally, dehydration secondary to gastrointestinal upset (a common side effect of GLP-1 agonists) might hypothetically increase susceptibility to UTIs, though this remains speculative and not formally documented in clinical studies