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Interestingly, while we do not know the role of GLP-1 in this circuit on food reward several studies have explored the therapeutic potential of nigro-striatal GLP-1 action in animal models of Parkinson's disease (Harkavyi et al., Competing and confounding behaviors Certain limitations should always be considered when a suppression of ingestive or motivated behavior is obtained

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He said: Trials are very robust in trying to establish safety, that the drugs generally have substantial benefits that outweigh the risks

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