A., & Iasnetsov, V
You want to inject right in that tent so the needle will be going into an air pocket between the skin and the muscle
Andersen-Ranberg, K., Hier-Madsen, M., Wiik, A., Jeune, B
There are certain other reasons as well, like Use of drugs like minocycline, birth control pills, certain cancer chemotherapies, etc
By utilizing biocompatible and highly hydrophilic modifying groups, such as polyethylene glycol (PEG), hyaluronic acid (HA), and polyamine compounds (like polyethyleneimine, PEI), nanoparticles can increase the binding ability with glycoproteins on the bladder mucosal surface, prolonging the drug retention time in the bladder and reducing drug loss due to urine flushing
Matenchuk BA, Mandhane PJ, Kozyrskyj AL