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Dosing is individualized, but a typical protocol titrates from a starting dose up to a target dose over 2 to 4 weeks, injected 5 days on and 2 days off, in defined cycles with scheduled breaks between them

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Completed intakes are typically reviewed within 24 hours

To this solution, 10 L of 200 mM NH 4 HCO 3 aq., 20 L of MeOH/propionic anhydride (3/1), and 18 L of 28% ammonia solution were added stepwise