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Hepatic impairment/alcohol use: Consider 23 g/day ceilings, extend dosing intervals, and monitor LFTs for multi-day use

Magnesium: Involved in over 300 enzymatic reactions, including collagen synthesis and muscle relaxation

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Importantly, TNF type 1 receptor knockout mice are resistant to the initiation and progression of NAFLD in response to both high-carbohydrate and methionine- and choline-deficient diets 26,27