They also reported the crystal structure of human CBS complexed with AOAA, in which the oxime intermediate is stabilized by a newly formed hydrogen-bond network involving Thr146, Thr150, and Gln222 (Figure 4A) (Petrosino et al., 2022)
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For instance, while not common, intramuscular injections of vitamin B12 have been reported to cause life-threatening anaphylaxis