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[18] [19] Rapidly progressive neurologic deficits, gait disturbance, or confusion warrant urgent evaluation

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The fact that such a tiny change - just one DNA letter out of roughly 2.8 billion - was enough to produce a dramatic developmental outcome, "shows that non-coding DNA can have a profound effect on development and disease, study leader Nitzan Gonen from Bar-Ilan University in Israel said in a statement

Peptide Sequence (IUPAC Condensed): H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH

4), indicating possible neuronal swelling in Wfs1 KO animals