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Randomised withdrawal trials across this class consistently show substantial regain after discontinuation, with a 2026 review reporting that roughly two-thirds of lost weight is typically regained within a year of stopping, alongside reversal of some cardiometabolic improvements
[13] Because tretinoin potentiates ultraviolet-induced erythema, patients undergoing phototherapy or receiving photosensitizing drugs should avoid the cream to prevent exaggerated inflammatory reactions
KCNQ5 has an antisense orientation transcript, lncRNA KCNQ5-DT , overlapping with a CGI around the transcription start site (TSS) of KCNQ5
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