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There is considerable literature about the oddities of the prescribing habits of British doctors , the factors influencing them, and the attitudes of doctors to prescription, but there have been as far as we know, no attempts to compare quantitatively the expected amount prescribed, on the basis of good clinical practice, with that actually prescribed

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Numerous reaction pathways involved in the synthesis of small molecules, as well as the synthesis and catabolism of neurotransmitters involve enzymes that are SAM-dependent methyltransferases