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FGF21 normalizes plasma glucose in mouse models of type 1 diabetes and insulin receptor dysfunction

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Fifth, due to limited numbers of study subjects in different individual GLP-1RA and insulin therapies, further assessment of comparative effectiveness and cost-effectiveness of treatments by the more granular level of different individual drugs would be underpowered

This gradual titration helps minimise gastrointestinal adverse effects, which are among the most commonly reported side effects

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doi: 10.1038/nrc3038 8 KommaganiRSzwarcMMKovanciEGibbonsWEPutluriNMaitySet al