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Hydrolysis pathway: The peptide bonds in glycine-histidine-lysine can hydrolyze in water over time, especially at pH extremes (below 4.0 or above 9.0)

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GSH biosynthesis is generally performed by two consecutive ATP-consuming reactions catalyzed by -glutamylcysteine synthetase (-GCS, GSHI) and glutathione synthetase (GS, GSHII) from three precursors in microorganisms: l-glutamate, l-cysteine, and glycine [1]

10.1002/mds.23455 Mov